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While their overall limb volume decreased enough that they needed small garments, they still need to wear compression most of the day and night, and still experience flare-ups when they don’t wear garments or with travel
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In contrast, human GIPR mRNA was exclusively detectable in GIPR/GLP1R double humanized mice (B-hGIPR/hGLP1R, H/H) but not in wild-type controls
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